Mirko and Michele Daneluzzo, the founders of Nyxo Design Studio, will be lecturing and showcasing some of the studio’s creative works at the upcoming online conference, Computational Design: NEXT 13. NYXO is a design company founded in 2015 by Mirko and Michele Daneluzzo. Their design agenda consists of the understanding and management of intricate transdisciplinary scenarios, using material systems and production processes as mediators. The research interest consists, on the one hand, in the use of digital computational and fabrication tools to set up apparatuses of simulation that can offer new aesthetic languages and are capable of re-territorialize the products in a posthuman, bio-integrated fashion. On the other hand, it is about the impact of the transformation of the artifacts from prostheses to bodies, in other words, from objects that are extensions of the human body to other bodies capable of autonomous agency. NYXO explores various technologies and typologies of artifacts, from serial products to research projects, for companies operating in different fields, from aeronautics to medical devices. The independent research of the studio focuses on the application of additive manufacturing technologies for End-Use productions at different scales. The architectural investigation develops the interweaving of bio-geo-climatic dynamics in the morphogenesis of spaces for a fusion with the local context. NYXO’s work has been exhibited internationally in several events including the Architecture Biennale in Venice 2010, Beijing 2010, and Tallinn 2017, in museums like the Cooper Hewitt, Smithsonian Design Museum, and in different Design Weeks, including Tokyo, Dubai, and Shanghai.